Oral Presentations
and Posters
Solved problems and unsolved challenges in applied human pharmacology
AGAH Annual Meeting 2010, Hamburg, February 21 - 23
Clinical Pharmacology of HX575, the first approved biosimilar epoetin alfa in Europe.
IXth World Conference on Clinical Pharmacology and Therapeutics, Quebec City, Canada,
27. July - 1. August, 2008. Abstract T2TH042
Clinical development programmes for biosimilars.
Plenary lecture, AGAH Annual Meeting 2008, Weimar, April 18 and 19, 2008
Drug Interactions: Gefährdung der Substitution
Plenary lecture, Symposium Beigebrauch Offene Grenzen der Substitution, Berlin, 19. and 20. May 2000
Stellenwert der Toxikokinetik im "Risk-Benefit Assessment"
Phytopharmakaforschung 2000 Forschungsergebnisse zu Qualität, Wirksamkeit und
Unbedenklichkeit.
Gemeinsames Symposium der Gesellschaft für Phytotherapie e.V. und der Gesellschaft für
Arzneipflanzenforschung e.V. Bonn 27.-28.11.1998
http://www.phytotherapy.org/kongress1998.htm
European studies in women's health.
Plenary lecture, 57th International Congress of FIP, World Congress of Pharmacy and Pharmaceutical
Sciences ‘97, Vancouver Canada, 31st August - 5th September 1997
U. LANG, M. WARGENAU, H. SOURGENS:
Sertraline, like other SSRIs, is a significant inhibitor of desipramine metabolism in vivo.
Br J Clin Pharmacol 39, 550P-551P, 1995
H. COLLIE, H. SOURGENS:
High Bioavailability and Rapid Distribution of Penciclovir Following an Oral Dose of Famciclovir.
Antiviral Research 26, A339-A339, 1995
http://www1.elsevier.com/cdweb/views/article.htm?jnl=01663542&iss=3&vol=26&pii=016635429594914
Schwangerschaft im Rahmen klinischer Studien, eine medizinische Indikation zum
Schwangerschaftsabbruch?
Vortrag, Herbsttagung der AGAH, Göttingen 1994
Entwicklung gastrointestinaler Arzneimittel.
Vortrag, Jahrestagung der AGAH Köln 1993
W. GREB, M. BRETT, H. COLLIE, J. KURTH:
Pharmacokinetics of granisetron (BRL 43694A) in man before and after enzyme induction by
phenobarbital.
5th World Conference on Clinical Pharmacology and Therapeutics, Yokohama, Japan, 26.-31.07.1992.
Abstract P-405-01
Verlängerte Tragzeit bei Ratten Uje: WIST durch Störungen während der Trächtigkeit, Assoziation mit
verzögerter Fetalentwicklung.
Vortrag zum 6. Symposium der AG Teratologie 27.-30.9.1989, Greifswald
Influence of treatment with lithium during pregnancy on reproductive performance of Fl-female rats.
Sixth International Symposium on Molybdenum, Vanadium and other Trace Elements, Jena, July 1989
Jodine deficiency and substitution - effects on fetal and postnatal thyroid function in the rat.
Sixth International Symposium on Molybdenum, Vanadium and other Trace Elements, Jena, July 1989
WITTKOWSKI W.:
Perinatal development of pituitary hormone production in relation to thyroid gland function.
VII. Symposium on Developmental Pharmacology, Reinhardsbrunn Castle, May 2-5 1989
A study to test the effect of diproteverine on the thyroid in normal volunteers.
Poster presentation, The British Toxicology Society and the Society for Drug Research, Churchill
College, Cambridge, 12-14 April 1989
Predictivity of animal models for endocrine toxicity.
Plenary lecture, The British Toxicology Society and the Society for Drug Research, Churchill College,
Cambridge, 12-14 April 1989
WITTKOWSKI W.:
Adverse effects of 7 Dimethyl-6-Deoxytetracycline (Minocycline) on the thyroid gland of the rat.
Naunyn-Schmiedeberg's Arch. Pharmacol., suppl. to Vol. 339, R 76, 1989
A study to test the effect of diproteverine on the thyroid in normal volunteers.
Poster presentation, The British Toxicology Society and the Society for Drug Research, Churchill
College, Cambridge, 12-14 April 1989
Predictivity of animal models for endocrine toxicity.
Plenary lecture, The British Toxicology Society and the Society for Drug Research, Churchill College,
Cambridge, 12-14 April 1989
Adverse effects of 7 Dimethyl-6-Deoxytetracycline (Minocycline) on the thyroid gland of the rat.
Naunyn-Schmiedeberg's Arch. Pharmacol., suppl. to Vol. 339, R 76, 1989
Perinatal development of pituitary hormone production; morphological and functional aspects and the
role of thyroid function.
Acta endocrinologica suppl. 1 p 212, 1989
Changes in the TSH-like immunoreactivity of the fetal pars tuberalis after maternal administration of
propyithiouracil (PTU), thyroxine (T4), caffeine and serotonin precursor tryptophan.
Acta endocrinologica suppl. 1 p 216, 1989
Endokrine Regulationen - Modulation durch Phytopharmaka.
2. Tagung der Gesellschaft für Phytotherapie, Münster, 20.- 22.10.1988
KEMPER F.H.:
Hemmung der Schilddrüsensekretion durch Pflanzeninhaltsstoffe; Untersuchung zur Struktur-
Wirkungs-Beziehung.
2. Tagung der Gesellschaft für Phytotherapie, Münster, 20.- 22.10.1988
Beeinflussung der antihormonalen Wirksamkeit von Lycopus europaeus durch Neurotransmitter.
2. Tagung der Gesellschaft für Phytotherapie, Münster, 20.- 22.10.1988
F.H. KEMPER:
Effects of maternal tryptophan and caffeine exposure on fetal development in relation to thyroid
activity in the rat.
European Society for Developmental Pharmacology, 1st Congress, April 21 - 23, Les Diablerets, 1988
Pharmakodynamik des Jod unter besonderer Berücksichtigung der Strumatherapie.
Jena, März 1988 - Vortrag vor der Arbeits- und Forschungsgemeinschaft Perinatologie an der Univ.
Kinderklinik.
F.H. KEMPER:
Perinatal effects of maternal caffeine exposure in relation to thyroid activity in the rat.
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 337, R. 82, 1988
Fetal thyroid gland morphology in iodine deficiency and after treatment with thyroid hormone
agonists.
32. Symposion Deutsche Gesellschaft für Endokrinologie, Hamburg, 1988
The impact of the hair dye component 2,4-diaminoanisole on thyroid gland functions and its
regulation.
Eurotox, Straßburg, 1987
G. UTHE-KASSENBROCK:
Adverse effects of UV-filters on the thyroid gland.
Eurotox, Straßburg, 1987
Black thyroid syndrome due to the hair dye component 2,4-diaminoanisole and its relation to hormonal
changes in the rat.
European Thyroid Association, Lausanne, 1987
Role of Iodide and Thyroid Hormones in fetal lung maturation in the rat.
First European Congress of Endocrinology, Copenhagen, 1987
Lead exposure and endocrine functions: Impact on the hypophyseal-gonadal axis and the pituitarythyroid
system.
Acta endocrin., Suppl. 283, Vol. 114, 17 - 18, 1987
TSH-stimulated secretion and its relation to thyroid function in the rat.
Acta endocrin., Suppl. 283, Vol. 114, 82 - 83, 1987
Beeinflussung der sekretorischen Aktivität der Schilddrüse. Lungenreifung und Schilddrüsenfunktion.
Jena, Oktober 1986 - Vortrag vor der Medizinischen Fakultät und der Arbeits- und
Forschungsgemeinschaft Perinatologie
Interference of cinnamic acid derivatives and Lycopus europ. with the neuroendocrine control of
prolactin and TSH in the rat.
Joint Meeting of the German Pharmacological Society and the Swiss Society for Pharmacology and
Toxicology, Mannheim, September 1986
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 334, R 41, 1986
A Pharmacological approach to the inhibition of the thyroidal secretion.
Joint Meeting of the German Pharmacological Society and the Swiss Society for Pharmacology and
Toxicology, Mannheim, September 1986
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 334, R 40, 1986
F.H. KEMPER:
Physiological and pharmacological regulation of thyroidal secretion in the rat.
Joint Meeting of the German Pharmacological Society and the Swiss Society for Pharmacology and
Toxicology, Mannheim, September 1986
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 334, R 40, 1986
H. SOURGENS and M. VOLKENANDT:
Influence of photoperiod on morphology and immunoreactivity of hypophysial pars tuberalis of the
Djungarian Hamster, Phodopus Sungorus.
Anatomie Kongress, Gießen 1986
Iodine and autoregulation of thyroid gland function: Inhibition of secretion and excess secretion of
thyroid hormones in rat and man.
5th International Symposium on Iodine and Other Trace Elements Jena, July 1986
Inhibition of endocytosis in highly stimulated thyroid follicles in vivo.
15. Annual Meeting of the European Thyroid Association, Stockholm, June 1986
Annales d'endocrinologie Vol.47, 111 A
Blei und Endokrinium
V. Symposium über Spurenelemente Münster, April 1986
Morphologic effects of the hair-dye component 2,4 diaminoanisole on the rat thyroid and its relation to
hormonal changes.
30. Symposium Deutsche Gesellschaft für Endokrinologie München, März 1986
Acta Endocrinologica, Vol. 111, Suppl. 274, 1986
Fetal lung maturity and thyroid hormone status.
Joint Meeting of the Belgian, Dutch, and German Pharmacological and Toxicological Societies
Aachen, September 1985
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 330, R19, 1985
Effects of the hair-dye component 2,4-diaminoanisole on the endocrine system and behavior.
Joint Meeting of the Belgian, Dutch, and German Pharmacological and Toxicological Societies
Aachen, September 1985
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 330, R19, 1985
Effects of maternal medication (3'Isopropyl-3,5-dimethyl-L-thyronine (DIMIT), Dexamethasone, 3(4'
CH3 Benzyliden)-campher and Iodide on fetal thyroid hormone status and fetotoxicity in the rat.
Verne Colloque International de Pharmacologie du Developpement Lyon, Juin 1985
Adverse effects of the hair-dye component 2,4-diaminoanisole on the thyroid gland of the rat.
26. Frühjahrstagung der Deutschen Pharmakologischen Gesellschaft, Mainz, März 1985
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 329, R24, 1985
The relative merits of prolactin-determinations in toxicological routine studies in the rat.
Kleinkonferenz "Prolactin im Tierversuch" der Arbeitsgruppe "Klinische Chemie bei
Laboratoriumstieren" der Deutschen Gesellschaft für Klinische Chemie, Rödermark, November 1984
J. Clin. Chem. Clin. Biochem. 1984
Beeinflussung des Hypophysenvorderlappenhormons Prolaktin durch Lycopus europaeus (Lamiaceae).
32. Vortragstagung der Arzneipflanzenforschung, Antwerpen, Juli 1984
Farmaceutisch Tijdschrift voor Belgie 61, 312-313, 1984
In-Vivo-Testung von Lycopus europaeus und verschiedenen Zimtsäure-Derivaten hinsichtlich eines
direkten Einflusses auf die sekretorische Aktivität der Schilddrüse.
32. Vortragstagung der Arzneipflanzenforschung, Antwerpen, Juli 1984
Farmaceutisch Tijdschrift voor Belgie 61, 253, 1984
V. v. LOEWENICH, M. BIELICKI and M. MÜLLER:
T4- and TSH-levels in methylxanthine - exposed premature and healthy newborns.
Symposium "Plasmakonzentration - Wirkungsbeziehung von Pharmaka", Stuttgart, Mai 1984
Benefit-risk-assessment of povidone-iodine (PVP-J) as hygienic desinfectant in geographic areas of
iodine deficiency.
Thyroid disorders, iodine deficiency and excess, Serono Symposium, Freiburg, April 1984
T3-Hyperthyroidism and goiter in the rat induced by medicinal plant extracts.
25. Frühjahrstagung der Deutschen Pharmakologischen Gesellschaft, Mainz, März 1984
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 325, R29, 1984
M. BIELICKI and M. MÜLLER:
Do methylxanthines influence T4- and TSH-levels in premature infants as compared to healthy
newborn and asthmatics?
Joint Meeting of the French and German Pharmacological and Toxicological Societies, Freiburg i.Br.,
September 1983
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 324, R78, 1983
Investigations on the structure-function-relationship and the antigonadotropic activity of phenolic
compounds.
Joint Meeting of the French and German Pharmacological and Toxicological Societies, Freiburg i.Br.,
September 1983
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 324, R58, 1983
Effects of Lycopus europaeus extracts on the serotoninergic transmission of TSH- and Prolactin release
in the rat.
Joint Meeting of the French and German Pharmacological and Toxicological Societies, Freiburg i.Br.,
September 1983
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 324, R56, 1983
The thyroidal secretion inhibiting effect of thyroid hormone metabolites, plant constituants and
Lithium chloride can be abolished by subsequent TSH-application.
Joint Meeting of the French and German Pharmacological and Toxicological Societies, Freiburg i.Br.,
September 1983
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 324, R56, 1983
N. BIELICKI:
T4-levels in methylxanthine treated premature newborns.
International Symposium on Pediatric Clinical Pharmacology, Düsseldorf, Mai 1983
F.H. KEMPER:
Observation on the interrelation between thyroid and thymus function in the toxicological screening
process.
Deutsche Pharmakologische Gesellschaft, Deutsche Physiologische Gesellschaft, Joint Spring
Meeting, Mainz, März 1983
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 322, R59, 1983
The effects of Lycopus virginicus and other plant extracts on the binding of TSH to human thyroid
plasma membranes and on adenylate cyclase activation.
26. Symposium Deutsche Gesellschaft für Endokrinologie, Salzburg, Februar 1982
Acta Endocrinol. (Kbh.) 99, Suppl. 246, 1982
W. NIEMANN:
PVP-iodine containing antiseptics interfere with thyroid hormone economy after cutaneous
application.
23. Frühjahrstagung der Deutschen Pharmakologischen Gesellschaft, Mainz, März 1982
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 319, R88, 1982
Inhibition of the binding of TSH and Graves'-IgG to human thyroid membranes by certain plant
extracts.
American Thyroid Association, 57th Meeting, Minneapolis, September 1981
Endocrinology, Suppl. to Vol. 109, T 17, 1981
H. WINTERHOFF, H. SOURGENS and H.G. GUMBINGER:
Plant inhibitors of iodothyronine deiodinases.
14th FEBS Meeting, Edinburgh, April 1981
Biochem. Society Transactions 9, 3248, 1981
H. SOURGENS and H.G. GUMBINGER:
lodothyronine deiodinases: Inhibition by plant extracts.
25. Symposium Deutsche Gesellschaft für Endokrinologie, Berlin, März 1981
Acta Endocrinol. (Kbh.) 96, Suppl. 240, 1981
Antithyroidal properties of Lithospermum officinale and related plants.
25. Symposium Deutsche Gesellschaft für Endokrinologie, Berlin, März 1981
Acta Endocrinol. (Kbh.) 96, Suppl. 240, 1981
Differences in the pharmacodynamic effects of freeze dried plant extracts against hypophyseal and
thyroid hormones in the rat.
22. Frühjahrstagung der Deutschen Pharmakologischen Gesellschaft, Mainz, März, 1981
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 316, R49, 1981
Zur Isolierung antigonadotrop wirksamer Inhaltsstoffe aus verschiedenen Arten der Gattungen
Lithospermum und Lycopus.
International Research Congress on Natural Products as Medical Agents, Straßburg, Juli 1980
Planta Medica 39, 245, 1980
Wirkprofile verschiedener Boraginaceen und Lamiaceen im Hypophysenvorderlappen-
Schilddrüsensystem der Ratte.
International Research Congress on Natural Products as Medical Agents, Straßburg, Juli 1980
Planta Medica 39, 245-246, 1980
R. MENDES and F.H. KEMPER:
Antihormonal effects of plant extracts on hypophyseal hormones in the rat.
24. Symposion Deutsche Gesellschaft für Endokrinologie, Berlin, Juni 1980
Acta Endocrinol. (Kbh.) 94, Suppl. 234, 1980
Interaction of different plant ingredients with hypothalamic-hypophyseal hormones in the rat.
21. Frühjahrstagung der Deutschen Pharmakologischen Gesellschaft, Mainz, März 1980
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 311, R53, 1980
F.H. KEMPER:
Effect of acute and chronic application of antihormonal plant extracts.
Acta-Endocrinologica Kongreß, München, Juni 1979
Acta Endocrinol. (Kbh.) 91, Suppl. 225, 1979
Further investigations on the mechanism of action of freeze dried extracts of Lithospermum officinale L.
20. Frühjahrstagung der Deutschen Pharmakologischen Gesellschaft, Mainz, März 1979
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 3o7, R51, 1979
F.H. KEMPER:
Influence of plant extracts on pituitary-thyroid interplay and peripheral thyroid hormone metabolism.
9. Jahrestreffen der European Thyroid Association, Berlin, September 1978
Annales d'endocrinologie 39, 14 A, 1978
K. NIEHAUS:
Zur antigonadotropen und antithyreotropen Wirkung von Pflanzenextrakten.
International meeting on medical plant research, Münster, Mai 1978
Planta Medica 33, 311, 1978
F. AENSTOOTS:
Pharmakodynamische Wirkungen von Lithospermum officinale auf den Schilddrüsenstoffwechsel bei
Ratten.
19. Frühjahrstagung der Deutschen Pharmakologischen Gesellschaft, Mainz, März 1978
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 302, R45, 1978
Influence of different buffer systems on the accuracy of thyroid hormone determination.
18. Frühjahrstagung der Deutschen Pharmakologischen Gesellschaft, Mainz, März 1977
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 297, R42, 1977
The predictive value of animal experiences in the detection of side effects of drugs on thyroid function
in men.
International workshop on pharmacological methods in preclinical safety evaluation of new drugs,
Zürich, Oktober 1977
The value of screening methods for the detection of thyroid "side-effects".
International workshop on pharmacological methods in preclinical safety evaluation of new drugs,
Zürich, Oktober 1977
On the radioimmunological determination of thyroid hormones.
17. Frühjahrstagung der Deutschen Pharmakologischen Gesellschaft, Mainz, März 1976
Naunyn-Schmiedeberg's Arch. Pharmacol., Suppl. to Vol. 293, R38, 1976
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